P
Pulse Beacon

Can nifedipine cause muscle pain

Author

John Castro

Published Apr 17, 2026

SIDE EFFECTS: Dizziness, flushing, weakness, swelling ankles/feet, constipation, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Can nifedipine cause muscle weakness?

SIDE EFFECTS: Dizziness, flushing, weakness, swelling ankles/feet, constipation, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What are the most common side effects of nifedipine?

  • Bloating or swelling of the face, arms, hands, lower legs, or feet.
  • difficult or labored breathing.
  • dizziness or lightheadedness.
  • fast, irregular, pounding, or racing heartbeat or pulse.
  • feeling of warmth.
  • headache.
  • muscle cramps.
  • shakiness in the legs, arms, hands, or feet.

Does blood pressure medication affect muscles?

Weakness, leg cramps, or fatigue. Diuretics may decrease the body’s levels of the mineral potassium, which can lead to these side effects. Certain potassium-sparing diuretics do not have this effect, however.

Can medications cause muscle pain?

Statin drugs are known to cause muscle pains and inflammation around the muscle cells (myositis). It should also be noted that the risk of muscle injury is greater when a statin is combined with other drugs that also cause muscle damage by themselves.

What are the side effects of nifedipine 20 mg?

  • headache.
  • nausea.
  • dizziness or lightheadedness.
  • flushing.
  • heartburn.
  • fast heartbeat.
  • muscle cramps.
  • constipation.

How long does it take for nifedipine to leave your system?

The elimination half-life of nifedipine is approximately two hours. Only traces (less than 0.1% of the dose) of unchanged form can be detected in the urine. The remainder is excreted in the feces in metabolized form, most likely as a result of biliary excretion.

What medications can cause joint and muscle pain?

  • 1) Antibiotic — levofloxacin. …
  • 2) Cholesterol-lowering medications — statins. …
  • 3) Osteoporosis medication — risedronate. …
  • 4) Asthma inhaler — fluticasone. …
  • 5) Breast cancer medications — anastrozole, exemestane, letrozole.

Can blood pressure meds cause muscle and joint pain?

(13) Blood Pressure Medication This “beta-blocker” relaxes the muscle cells in the heart and blood vessels to lower blood pressure. It will cause joint and back pain in about 6% of its users.

What causes muscle cramps all over the body?

Overuse of a muscle, dehydration, muscle strain or simply holding a position for a prolonged period can cause a muscle cramp. In many cases, however, the cause isn’t known. Although most muscle cramps are harmless, some may be related to an underlying medical condition, such as: Inadequate blood supply.

Article first time published on

What is a good replacement for nifedipine?

Nisoldipine appears to be an effective substitute treatment for nifedipine in severely hypertensive patients sensitive or resistant to nifedipine.

How can I reduce the side effects of nifedipine?

  1. Take the prescribed dose of nifedipine. …
  2. Disclose your full medication list and health history. …
  3. Store nifedipine correctly. …
  4. Do not suddenly stop taking nifedipine. …
  5. Avoid certain foods and supplements. …
  6. Seek immediate medical attention for allergic symptoms or overdose.

Is 60 mg of nifedipine a lot?

The usual maximum doses of nifedipine are: short acting capsules or liquid: 20mg 3 times a day (total of 60mg a day) long acting capsules or tablets: 40mg twice a day or 90mg once a day (total of 80mg or 90mg a day)

When should I be worried about muscle pain?

Get immediate medical care if you have muscle pain with: Trouble breathing or dizziness. Extreme muscle weakness. A high fever and stiff neck.

What medications cause leg muscle pain?

  • Short-acting loop diuretics. …
  • Thiazide diuretics. …
  • Beta-blockers. …
  • Statins and fibrates. …
  • Beta2-agonists. …
  • ACE inhibitors. …
  • Angiotensin II-receptor blockers (ARBs) …
  • Antipsychotics.

How do you relieve muscle pain from medication?

  1. resting the area of the body where you’re experiencing aches and pains.
  2. taking an over-the-counter pain reliever, such as ibuprofen (Advil)
  3. applying ice to the affected area to help relieve pain and reduce inflammation.

Has nifedipine been discontinued?

Bayer have announced plans to permanently discontinue nifedipine immediate-release 5mg & 10mg capsules (Adalat) in 2019.

Can I take ibuprofen with nifedipine?

ibuprofen NIFEdipine The combination may cause your blood pressure to increase. You may need a dose adjustment or your blood pressure checked more often. Also, if you are already taking the combination and stop taking ibuprofen, your blood pressure may decrease.

Which is better amlodipine or nifedipine?

Amlodipine was better tolerated than nifedipine, as shown by the lower incidence of side effects. Therefore amlodipine proved to be an effective and well tolerated drug in the therapy of mild to moderate hypertension.

What medications interact with nifedipine?

Strong CYP3A inducers, such as rifampin, rifabutin, phenobarbital, phenytoin, carbamazepine, and St. John’s Wort reduce the bioavailability and efficacy of nifedipine; therefore nifedipine should not be used in combination with strong CYP3A inducers such as rifampin (See CONTRAINDICATIONS).

Can you take Tylenol with nifedipine?

No interactions were found between nifedipine and Tylenol. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

What medications cause muscle stiffness?

  • Lipitor (atorvastatin calcium) Lipitor lowers levels of bad cholesterol and increases levels of good cholesterol. …
  • Glucophage (metformin) …
  • Klonopin (clonazepam) …
  • Ambien (zolpidem) …
  • Xanax (alprazolam) …
  • Ultram (tramadol) …
  • Omeprazole.

What is the safest blood pressure medication with the least side effects?

Thiazide diuretics generally have fewer side effects than the others. This is especially true when they’re prescribed in the low doses that are generally used in treating early high blood pressure. Examples of thiazide diuretics include: chlorthalidone (Hygroton)

What is a common side effect of many blood pressure medications?

  • Cough.
  • Diarrhea or constipation.
  • Dizziness or lightheadedness.
  • Erection problems.
  • Feeling nervous.
  • Feeling tired, weak, drowsy, or a lack of energy.
  • Headache.
  • Nausea or vomiting.

What is the best tablet for muscle pain?

Drug nameRatingRx/OTCView information about Paracetamol Paracetamol9.7Rx/OTCGeneric name: acetaminophen systemic Drug class: miscellaneous analgesics For consumers: dosage, interactions, side effectsView information about Advil Advil6.2Rx/OTC

What medications cause muscle fatigue?

  • amiodarone (Cordarone)
  • antithyroid medications, such as methimazole (Tapazole) or propylthiouracil.
  • antiretroviral medicines, such as lamivudine (Epivir) or zidovudine (Retrovir)
  • chemotherapy medications.
  • cimetidine (Tagamet)
  • corticosteroids.

What are 5 common causes of muscle cramps?

  • Straining or overusing a muscle. …
  • Compression of your nerves, from problems such as a spinal cord injury or a pinched nerve in the neck or back.
  • Dehydration.
  • Low levels of electrolytes such as magnesium, potassium, or calcium.
  • Not enough blood getting to your muscles.
  • Pregnancy.
  • Certain medicines.

What disease causes muscle cramps?

People living with diabetes, liver disorders, nerve compression, and thyroid disorders may experience muscle cramps. Women who are pregnant tend to experience hamstring and other muscle cramps.

What deficiency causes muscle cramps?

Having a magnesium deficiency can be a cause of muscle cramps. And it’s common for people to need more magnesium.

How much Nifedipine is safe?

Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

What are the side effects of nifedipine ER 60 mg?

  • headache.
  • nausea.
  • dizziness or lightheadedness.
  • flushing (reddening of the skin)
  • heartburn.
  • muscle cramps.
  • constipation.
  • cough.